Dihydrosphingosine

(HB0247)

Product overview

  • Name
    Dihydrosphingosine
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor. Shows vasodilatory actions.
  • Alternative names
    Sphinganine
  • Biological action
    Inhibitor
  • Citations

Properties

  • Chemical name
    DL-erythro-1,3-Dihydroxy-2-aminooct adecane
  • Molecular Weight
    301.51
  • Chemical structure
    Dihydrosphingosine  [3102-56-5]
  • Molecular Formula
    C18H39NO2
  • CAS Number
    3102-56-5

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Dihydrosphingosine

  • Effects of exogenous sphinganine, sphingosine, and sphingosine-1-phosphate on relaxation and contraction of porcine thoracic aortic and pulmonary arterial rings.

    Hsiao SH et al (2005) Toxicol Sci 86(1) : 194-9.
    PubMedID: 15829618
  • Sphinganine potentiation of dimethyl sulfoxide-induced granulocyte differentiation, increase of alkaline phosphatase activity and decrease of protein kinase C activity in a human leukemia cell line (HL-60).

    Yung BY et al (1994) Biochem Biophys Res Commun 199(2) : 888-96.
    PubMedID: 8135836
  • Protein kinase C mediated anti-proliferative glucocorticoid-sphinganine synergism in cultured Pollard III prostate tumor cells.

    Sosnowski J et al (1997) J Urol 158(1) : 269-74.
    PubMedID: 9186373

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