Widely used solvent. Improves direct differentiation of pluripotent stem cells and used as a stem cell cryoprotectant
Organic solvent widely used for dissolving lipophilic substances.
Commonly used as a cryototectant in cryopreservation of stem cells.
DMSO activates the retinoblastoma (Rb) protein and increases the proportion of cells in the early G1 phase of the cell cycle.
DMSO improves directed differentiation of many cell lines. DMSO increases the competency of pluripotent stem cells (in >25 different embryonic and induced pluripotent stem cell lines) to respond to differentiation signals, enhance differentation across all germ layers and improve terminal differentiation into functional derivatives
Endotoxin < 0.05 I.E(EU)/mL
Methyl sulfoxide, Dimethyl Sulfoxide
Storing and Using Your Product
Room temperature (desiccate)
This compound is light sensitive. We therefore recommend protecting the compound and solutions from light.
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for DMSO (Sterile-filtered)
Cryopreservation of hematopoietic stem cells.Berz et al (2007) Am J Hematol 82(6): : 463-72PubMedID: 17266054
A simple tool to improve pluripotent stem cell differentiation.Chetty et al (2013) Nat Methods 10(6) : 553-6PubMedID: 23584186
A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cells.Ogaki et al (2015) Sci Rep 30 : 5:17297PubMedID: 26616277
Reviews & Product Guides
Good for vehicle solution. We used this DMSO to make vehicle solutions for i.p. injections. The 5 individual 10ml vials were a great option so that the vial could remain sterile.