DMSO (Sterile-filtered)

(HB3262)

Product overview

  • Name
    DMSO (Sterile-filtered)
  • Short description
    Widely used solvent. Improves direct differentiation of pluripotent stem cells. and used as a stem cell cryoprotectant
  • Biological description

    Organic solvent widely used for dissolving lipophilic substances.


    Commonly used as a cryototectant in cryopreservation of stem cells.


    DMSO activates the retinoblastoma (Rb) protein and increases the proportion of cells in the early G1 phase of the cell cycle.


    DMSO improves directed differentiation of many cell lines. DMSO increases the competency of pluripotent stem cells (in >25 different embryonic and induced pluripotent stem cell lines) to respond to differentiation signals, enhance differentation across all germ layers and improve terminal differentiation into functional derivatives 


    Endotoxin < 0.05 I.E(EU)/mL

  • Alternative names
    Methyl sulfoxide
  • Purity
    >99.9%
  • Citations

Properties

  • Chemical name
    Dimethyl sulfoxide
  • Molecular Weight
    78.13
  • Chemical structure
    DMSO [67-68-5]
  • Molecular Formula
    C2H6OS
  • CAS Number
    67-68-5
  • PubChem identifier
    679
  • SMILES
    CS(=O)C
  • InChi
    InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
  • InChiKey
    IAZDPXIOMUYVGZ-UHFFFAOYSA-N
  • MDL number
    MFCD00002089
  • Appearance
    colourless liquid

Storing and Using Your Product

  • Storage instructions
    Room temperature (desiccate)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for DMSO (Sterile-filtered)

  • Cryopreservation of hematopoietic stem cells.

    Berz et al (2007) Am J Hematol 82(6): : 463-72
    PubMedID: 17266054
  • A simple tool to improve pluripotent stem cell differentiation.

    Chetty et al (2013) Nat Methods 10(6) : 553-6
    PubMedID: 23584186
  • A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cells.

    Ogaki et al (2015) Sci Rep 30 : 5:17297
    PubMedID: 26616277