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Doxycycline hyclate

(HB4608)
Data

Product overview

  • Name
    Doxycycline hyclate
  • Short description
    Broad-spectrum antibiotic. Used in inducible Tet-on/ Tet-off gene expression systems.
  • Biological description

    Broad-spectrum antibiotic. Tetracycline analog. Also acts as a matrix metalloprotease (MMP) inhibitor. 

    Commonly used in the inducible Tet-on/ Tet-off gene expression system to control transcription. 

    Recently used to develop a doxycycline-inducible, viral mediated CRISPR/Cas9 system.

  • Alternative names
    DOX
  • Biological action
    Antibiotic
  • Applications
    Antineoplastic Agent
  • Purity
    >93%
  • Citations

Properties

  • Chemical name
    (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)- 3,5,10,12,12a-pentahydroxy- 6-methyl- 1,11-dioxo- 1,4,4a,5,5a,6,11,12a-octahydrotetracene- 2-carboxamide hydrochloride hemiethanolate hemihydrate
  • Molecular Weight
    512.94
  • Chemical structure
    Doxycycline hyclate [24390-14-5]
  • Molecular Formula
    C22H24N2O8.HCl.0.5H2O.0.5C2H6O
  • CAS Number
    24390-14-5
  • PubChem identifier
    54686898
  • SMILES
    CCO.C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
  • InChi
    InChI=1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10+,14+,15-,17-,22-;;;;/m00..../s1
  • InChiKey
    OJMDBNRHBLXJLF-LJTDZVLQSA-N
  • MDL number
    MFCD07357237
  • Appearance
    Pale yellow to yellow

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in DMSO (100 mM) and water (100 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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