Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Potent adenosine deaminase (ADA) and PDE2 inhibitor (Ki = 1.6 nM at ADA and IC50 values are 0.8 and 4 ΜM at human and porcine PDE2 respectively. Reversibly supresses spontaneous hESCs differentiation. Also acts as a strong blocker of directed neuronal differentiation.
Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
Soluble in water (100mM) or DMSO (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.