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Solubility & Handling
| Storage instructions | -20°C (desiccate) |
| Solubility overview | Soluble in water (1 mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
| Chemical name | CSCSSLMDKECVYFCHLDIIW
(Disulfide bridge between 1 - 15, 3 - 11) |
| Chemical structure | ![Endothelin 1 (human, porcine) [117399-94-7] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Endothelin 1 (human, porcine) [117399-94-7]") |
| Molecular Formula | C109H159N25O32S5 |
| Sequence (one letter) | CSCSSLMDKECVYFCHLDIIW |
| Sequence (three letter) | Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp |
| Modifications | Disulfide bridge between 1 - 15, 3 - 11 |
| PubChem identifier | 16133807 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N |
| InChiKey | ZUBDGKVDJUIMQQ-ZTNLKOGPSA-N |
References for Endothelin 1 (human, porcine)
References are publications that support the biological activity of the product
-
Endothelin-1: Biosynthesis, Signaling and Vasoreactivity.
Houde et al (2016) Adv Pharmacol 77 : 143-75 -
The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis.
Kowalczyk et al (2015) Arch Immunol Ther Exp (Warsz) 63(1) : 41-52 -
Endothelin-1: the yin and yang on vascular function.
Marasciulo et al (2006) Curr Med Chem 13(14) : 1655-65
Endogenous vasoconstrictor neuropeptide
![Endothelin 1 (human, porcine) [117399-94-7] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3442_1.png "Endothelin 1 (human, porcine) [117399-94-7]")
Understanding purity and quality - a guide for life scientists
