In my cart

You have no items in your shopping cart.



Product overview

  • Name
  • Short description
    Potent, selective and irreversible 20S proteasome inhibitor
  • Biological description
    Antibiotic. Potent anticancer compound. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively). Anti-inflammatory. Antimicrobial and antimalarial. Anti-parasitic. Stimulates bone formation by inhibiting osteoblast proteasome activity. Induces Parkinson's-like symptoms in rats. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy.
  • Purity
  • Citations


  • Molecular Weight
  • Chemical structure
    Epoxomicin [134381-21-8]
  • CAS Number
  • InChiKey
  • Appearance
    White to off-white solid

Storing and Using Your Product

  • Storage instructions
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources

Reviews & Product Guides