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Eticlopride hydrochloride

(HB1873)
Data

Product overview

  • Name
    Eticlopride hydrochloride
  • Short description
    D2 receptor antagonist
  • Biological description
    D2 receptor antagonist which also shows some activity at D3 and D4 receptors (Ki values are 0.07, 0.16, 22.3 nM at D2, D3 and D4 respectively). Shows antipsychotic effects. Active in vivo.
  • Biological action
    Antagonist
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamid e hydrochloride
  • Molecular Weight
    377.31
  • Molecular Formula
    C17H25ClN2O3.HCl
  • CAS Number
    97612-24-3

Storing and Using Your Product

  • Storage instructions
    room temperature (desiccate)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Eticlopride hydrochloride

  • The D3 dopamine receptor: neurobiology and potential clinical relevance.

    Levant B (1997) Pharmacol Rev 49(3) : 231-52.
    PubMedID: 9311022
  • The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys.

    Claytor R et al (2006) Pharmacol Biochem Behav 83(3) : 456-64.
    PubMedID: 16631246
  • Involvement of dopamine receptors in the antipsychotic profile of (-) eticlopride.

    Giuliani D et al (1997) Physiol Behav 61(4) : 563-7.
    PubMedID: 9108576
  • Morphogenic potentials of D2, D3, and D4 dopamine receptors revealed in transfected neuronal cell lines.

    Swarzenski BC et al (1994) Proc Natl Acad Sci U S A 91(2) : 649-53.
    PubMedID: 7904756
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