FLUO 3/AM

(HB0772)

Product overview

  • Name
    FLUO 3/AM
  • Short description
    Cell permeable Ca2+ sensitive fluorescent indicator
  • Biological description
    Cell permeable Ca2+ sensitive fluorescent indicator (Kd = 0.36 µM). Metabolized by cytoplasmic esterases into FLUO-3.
  • Biological action
    Dyes & stains
  • Purity
    >85%
  • Citations

Properties

  • Molecular Weight
    1129.85
  • Chemical structure
    FLUO 3/AM  [121714-22-5]
  • Molecular Formula
    C51H50Cl2N2O23
  • CAS Number
    121714-22-5
  • PubChem identifier
    http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5086914
  • SMILES
    CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=C4C=C(C(=O)C=C4OC5=CC(=C(C=C53)Cl)OCOC(=O)C)Cl)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

Storing and Using Your Product

  • Solubility overview
    soluble in DMSO (0.9mg/ml) or water
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for FLUO 3/AM

  • Loading and localization of Fluo-3 and Fluo-3/AM calcium indicators in sinapis alba root tissue.

    Tretyn A et al (1997) Folia Histochem Cytobiol 35(1) : 41-51.
    PubMedID: 9090510
  • Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy.

    Orlick󠇬 J et al (2004) Gen Physiol Biophys 23(3) : 357-66.
    PubMedID: 15638123
  • Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics.

    Loughrey CM et al (2003) Cell Calcium 34(1) : 1-9.
    PubMedID: 12767887

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