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Fluvoxamine maleate

(HB2138)
Data

Product overview

  • Name
    Fluvoxamine maleate
  • Short description
    Selective serotonin reuptake inhibitor and σ1 receptor agonist
  • Biological description
    Selective serotonin reuptake inhibitor and σ1 receptor agonist (Ki = 36 nM at σ1). Shows antidepressant and anxiolytic activity. Active in vivo.
  • Alternative names
    NSC 309469
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    (E)-5-Methoxy-1-[4-(trifluoromethyl )phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
  • Molecular Weight
    434.41
  • Chemical structure
    Fluvoxamine maleate [61718-82-9]
  • Molecular Formula
    C15H21F3N2O2.C4H4O4
  • CAS Number
    61718-82-9
  • PubChem identifier
    9560989
  • SMILES
    COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F.C(=C\C(=O)O)\C(=O)O
  • InChi
    InChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
  • InChiKey
    LFMYNZPAVPMEGP-PIDGMYBPSA-N
  • MDL number
    MFCD00269809
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    +4°C (desiccate)
  • Solubility overview
    Soluble in water (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Fluvoxamine maleate

  • Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.

    Claassen et al (1977) Br J Pharmacol 60(4) : 505-16
    PubMedID: 302726
  • Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.

    Narita et al (1996) Eur J Pharmacol 307(1) : 117-9
    PubMedID: 8831113
  • Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.

    Benfield (1986) Drugs 32(4) : 313-34
    PubMedID: 3096686
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