Product overview

  • Name
    FPA 124
  • Short description
    Akt inhibitor
  • Biological description
    Akt (PKB) inhibitor (IC50 = 100 nM ). Inactivates NF-κB. Shows anti-proliferative actions.
  • Biological action
    Inhibitor
  • Our products in action

Properties

  • Chemical name
    Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamidecoppercomplex
  • Molecular Weight
    381.73
  • Chemical structure
    FPA 124  [902779-59-3]
  • Molecular Formula
    C11H9Cl2CuN3O2S
  • CAS Number
    902779-59-3

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in DMSO (10mM) or ethanol (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for FPA 124

  • Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.

    Barve V et al (2006) J Med Chem 49(13) : 3800-8.
    PubMedID: 16789737
  • Activation of protein kinase B/Akt by alpha1-adrenoceptors in the human prostate.

    Strittmatter F et al (2012) Life Sci 90(11-12) : 446-53.
    PubMedID: 22280833

Reviews & Product Guides