gamma-DGG / γ-DGG (γ-D-glutamylglycine)

(HB0680)
Technical documents: CoA Datasheet

Product overview

Name gamma-DGG / γ-DGG (γ-D-glutamylglycine)
Alternative names Gamma-D-glutamylglycine
Purity >99%
Description Broad spectrum glutamate antagonist
Write Your Own Review
You're reviewing:gamma-DGG / γ-DGG (γ-D-glutamylglycine)
Rate this item:

Images

γ-DGG (γ-D-glutamylglycine) product vial image | Hello Bio

Biological Data

Biological description

Broad spectrum glutamate antagonist. Low affinity, rapidly dissociating competitive AMPA receptor antagonist which blocks AMPAR-mediated EPSCs. Also an non-selective NMDA receptor antagonist. Shows anti-depressant actions.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in NaOH(aq) (100mM, gentle warming) or water (100mM, gentle warming)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >99%
Chemical name γ-D-Glutamylglycine
Molecular Weight 204.18
Chemical structure γ-DGG (γ-D-glutamylglycine)  [6729-55-1] Chemical Structure
Molecular Formula C7H12N2O5
CAS Number 6729-55-1
PubChem identifier 6604701
SMILES O=C(CC[C@@H](N)C(=O)O)NCC(=O)O
InChiKey ACIJGUBIMXQCMF-SCSAIBSYSA-N

References for gamma-DGG / γ-DGG (γ-D-glutamylglycine)

References are publications that support the biological activity of the product
  • Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons.

    Guzman RE et al (2014) Front Cell Neurosci 8 : 143
  • Glutamate neurotransmission in the cerebellar interposed nuclei: involvement in classically conditioned eyeblinks and neuronal activity.

    Aksenov DP et al (2005) J Neurophysiol 93(1) : 44-52.
  • Depressant actions of gamma-D-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord.

    Davies J et al (1985) Brain Res 327(1-2) : 113-20.

3 Item(s)