Product overview

  • Name
    GANT61
  • Short description
    GLI antagonist. Also Hedgehog (Hh) signaling inhibitor.
  • Biological description
    Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription. Additionally inhibits hedgehog (Hh) signaling pathway, downstream of SMO and SUFU. Displays antiproliferative, antitumor and apoptosis inducing activity. Also inhibits pluripotency maintaining factors c-Myc, Nanog, Oct4, Sox-2 in pancreatic cancer stem cells.
  • Biological action
    Antagonist
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    2,2'-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine
  • Molecular Weight
    429.6
  • Chemical structure
    GANT61 | NSC 136476  [500579-04-4]
  • Molecular Formula
    C27H35N5
  • CAS Number
    500579-04-4
  • InChiKey
    KVQOGDQTWWCZFX-UHFFFAOYSA-N
  • Appearance
    White to off-white solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.