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GD3 ganglioside disodium salt (bovine brain)

(HB3909)
Data

Product overview

  • Name
    GD3 ganglioside disodium salt (bovine brain)
  • Short description
    Glycosphingolipid ganglioside. Mitochondrial permeability transition inducer.
  • Biological description
    Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD3 induces mitochondrial permeability transition (MPT) without requiring elevated Ca2+ levels and thus triggers Fas-mediated apoptosis. It modulates the activity of Src-family tyrosine kinase Lyn and cell apoptosis. It is involved in several tumor processes and is high abundant in proliferating cells and in the first stage of neuronal differentiation.
  • Purity
    >98%
  • Citations

Properties

  • Molecular Weight
    1516.8
  • Chemical structure
    GD3 ganglioside disodium salt (bovine brain) [62010-37-1]
  • CAS Number
    62010-37-1
  • InChiKey
    LGRBZCLULGFXOD-MIJDSYIJSA-L
  • Appearance
    Lyophilized

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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