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Ghrelin (rat)

(HB2942)
Data

Product overview

  • Name
    Ghrelin (rat)
  • Short description

    Endogenous hormone. Ghrelin receptor agonist

  • Biological description

    Overview

    Ghrelin is an endogenous ghrelin (GHS) receptor agonist and is an orexigenic hormone.

    Uses & applications

    It stimulates growth hormone release from the pituitary gland and is involved in a range of biological activities.

    For example, it stimulates appetite and food intake and regulates of growth hormone and insulin secretion.

    Additionally, it is involved in glucose and energy homeostasis, gastrointestinal motility, cardioprotection and neurogenesis.

  • Biological action
    Peptide
  • Citations

Properties

  • Chemical name
    GSSFLSPEHQKAQQRKESKKPPAKLQPR (Ser-3 = Ser(n-octanoyl))
  • Molecular Weight
    3314.83
  • Chemical structure
    Ghrelin (rat) [258338-12-4]
  • Molecular Formula
    C147H245N45O42
  • Sequence (one letter)
    GSSFLSPEHQKAQQRKESKKPPAKLQPR
  • Sequence (three letter)
    Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
  • Modifications
    Ser-3 = Ser(n-octanoyl)
  • CAS Number
    258338-12-4
  • PubChem identifier
    44134734
  • SMILES
    CCCCCCCC(=O)N(C(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC=N3)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)N6CCCC6C(=O)NC(CCCNC(=N)N)C(=O)O)C(=O)C(CO)NC(=O)CN
  • InChiKey
    YQVMHOLUYGAYNG-UHFFFAOYSA-N
  • Protein length
    29

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    Soluble in water (1 mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

References for Ghrelin (rat)

  • An Integrative Review on Role and Mechanisms of Ghrelin in Stress, Anxiety and Depression

    Bali A et al (2016) Curr Drug Targets 17(5) : 495-507
    PubMedID: 25981609
  • Ghrelin: much more than a hunger hormone

    Pradhan G et al (2013) Curr Opin Clin Nutr Metab Care 16(6) : 619-24
    PubMedID: 24100676
  • Ghrelin: integrative neuroendocrine peptide in health and disease

    Wu JT et al (2004) Ann Surg 239(4) : 464-74
    PubMedID: 15024307
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