GT1b ganglioside trisodium salt (bovine brain)
Glycosphingolipid ganglioside. Binds botulinum and tetanus neurotoxins.
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GT1b binds botulinum and tetanus neurotoxins and it prevents neurotoxicity of glutamate on neuronal cells.
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.