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H 89 dihydrochloride

(HB0314)
Technical documents: SDS Datasheet

Product overview

Name H 89 dihydrochloride
Purity >99%
Description Potent, non-selective kinase inhibitor.Also improves dissociate hESCs survival and clonogenicity.
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Biological Data

Biological description Potent, non-selective kinase inhibitor. Protein kinase A inhibitor (IC50 = 135 nM). Also inhibits S6K1, MSK1, ROCKII, PKBα and MAPKAP-Klb (IC50 values are 80, 120 and 270 nM, 2.6 µM and 2.8 µM respectively). Also improves dissociate hESCs survival and clonogenicity.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (25mM) or DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamidedihydrochloride
Molecular Weight 519.28
Chemical structure H 89 dihydrochloride  [130964-39-5] Chemical Structure
Molecular Formula C20H20BrN3O2S.2HCl
CAS Number 130964-39-5
PubChem identifier 5702541
SMILES O=S(C2=CC=CC1=CN=CC=C12)(NCCNC/C=C/C3=CC=C(Br)C=C3)=O.Cl.Cl
InChiKey GELOGQJVGPIKAM-WTVBWJGASA-N

References for H 89 dihydrochloride

References are publications that support the biological activity of the product

4 Item(s)