Haloperidol hydrochloride

(HB1842)

Product overview

  • Name
    Haloperidol hydrochloride
  • Short description
    Dopamine receptor antagonist with partial D2-like selectivity
  • Biological description
    Dopamine receptor antagonist with partial D2-like receptor selectivity (Ki values are 0.53, 2.7, 2.3, 27 and 48 nM at D2, D3, D4, D1 and D5 receptors respectively). Shows variety of biological actions. Active in vivo.
  • Alternative names
    Haloperidol hydrochloride
  • Biological action
    Antagonist
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride
  • Molecular Weight
    412.33
  • Chemical structure
    Haloperidol hydrochloride  [1511-16-6]
  • Molecular Formula
    C21H23ClFNO2.HCl
  • CAS Number
    1511-16-6

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Haloperidol hydrochloride

  • Inhibition of N-methyl-D-aspartate receptors by haloperidol: developmental and pharmacological characterization in native and recombinant receptors.

    Lynch DR et al (1996) J Pharmacol Exp Ther 279(1) : 154-61.
    PubMedID: 8858988
  • Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects.

    Strange PG (2001) Pharmacol Rev 53(1) : 119-33.
    PubMedID: 11171942
  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

    Sunahara RK et al (1991) Nature 350(6319) : 614-9.
    PubMedID: 1826762

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