I-CBP 112

(HB1447)

Product overview

  • Name
    I-CBP 112
  • Short description
    CBP/p300 Bromodomain inhibitor
  • Biological description
    CBP/p300 Bromodomain inhibitor (IC50 values are 170 and 625 nM). Selective over ATAD2, BAZ2B, BRD2, BRD4, PB1, PCAF, PHIP and TRIM24/TIF-1a. Shows accelerated FRAP recovery at 1 µM.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
  • Molecular Weight
    468.59
  • Chemical structure
    I-CBP 112
  • Molecular Formula
    C27H36N2O5

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for I-CBP 112

  • Bromodomains and their pharmacological inhibitors.

    Gallenkamp D et al (2014) ChemMedChem 9(3) : 438-64.
    PubMedID: 24497428

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