Product overview

  • Name
    IHR-NAc
  • Short description
    Sonic hedgehog (Shh) signaling pathway inhibitor
  • Biological description
    Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane permeable Smoothened (Smo) antagonist. Acts on extra- and intracellular exposed Smo. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    5-Acetamido-2-chloro-N-[4-(2,5-dichlorobenzamido)phenyl]benzamide
  • Molecular Weight
    476.7
  • Chemical structure
    IHR-NAc
  • InChiKey
    KEKPTYABAFCFOT-UHFFFAOYSA-N
  • Appearance
    White to grey solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

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