In my cart

You have no items in your shopping cart.

(-)-Indolactam V


Product overview

  • Name
    (-)-Indolactam V
  • Short description
    Synthetic PKC activator
  • Biological description
    Synthetic protein kinase C (PKC) inhibitor. Also induces embryonic stem cell differentiation. Displays tumor promoting properties with mitogenic and comitogenic activating effects.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    (-)-Indolactam V  [90365-57-4]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in DMSO (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for (-)-Indolactam V

  • Synthesis and biological activities of indolactone-V, the lactone analogue of the tumor promoter (-)-indolactam-V.

    Nakagawa Y et al (1997) Biosci Biotechnol Biochem 61(8) : 1415-7.
    PubMedID: 9301127
  • (-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.

    Heikkilä J et al (1989) Biochem Biophys Res Commun 162(3) : 1207-13.
    PubMedID: 2764930
  • (-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways.

    Papadogiannakis N (1995) Cell Immunol 162(2) : 288-94.
    PubMedID: 7743557
  • A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

    Chen S et al (2009) Nat Chem Biol 5(4) : 258-65.
    PubMedID: 19287398
Support & Resources

Reviews & Product Guides