Indole-3-acetamide

(HB0341)

Product overview

  • Name
    Indole-3-acetamide
  • Short description
    Competitive Tryptophan 2-monooxygenase oxidase inhibitor
  • Biological description
    Competitive Tryptophan 2-monooxygenase inhibitor. Intermediate of indole-3-acetic acid formation from L-tryptophan. Detoxifies several growth inhibiting tryptophan analogs.
  • Alternative names
    3-Indolylacetamide; NSC 1969; IAM
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Molecular Weight
    174.2
  • Chemical structure
    Indole-3-acetamide  [879-37-8]
  • Molecular Formula
    C10H10N2O
  • CAS Number
    879-37-8
  • PubChem identifier
    397
  • SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(=O)N

Storing and Using Your Product

  • Solubility overview
    soluble in methanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Indole-3-acetamide

  • Biosynthesis of indole-3-acetic acid via the indole-3-acetamide pathway in Streptomyces spp.

    Manulis S et al (1994) Microbiology 140 ( Pt 5) : 1045-50.
    PubMedID: 8025670
  • Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase.

    Gadda G et al (1999) Biochemistry 38(18) : 5822-8.
    PubMedID: 10231533
  • Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.

    Dillard RD et al (1996) J Med Chem 39(26) : 5119-36.
    PubMedID: 9005255

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