Product overview

Name Indole-3-acetamide
Alternative names 3-Indolylacetamide; NSC 1969; IAM
Purity >98%
Description Competitive Tryptophan 2-monooxygenase oxidase inhibitor
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Biological Data

Biological description Competitive Tryptophan 2-monooxygenase inhibitor. Intermediate of indole-3-acetic acid formation from L-tryptophan. Detoxifies several growth inhibiting tryptophan analogs.

Solubility & Handling

Solubility overview Soluble in methanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 174.2
Chemical structure Indole-3-acetamide  [879-37-8] Chemical Structure
Molecular Formula C10H10N2O
CAS Number 879-37-8
PubChem identifier 397
SMILES C1=CC=C2C(=C1)C(=CN2)CC(=O)N

References for Indole-3-acetamide

References are publications that support the biological activity of the product
  • Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase.

    Gadda G et al (1999) Biochemistry 38(18) : 5822-8.
  • Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.

    Dillard RD et al (1996) J Med Chem 39(26) : 5119-36.
  • Biosynthesis of indole-3-acetic acid via the indole-3-acetamide pathway in Streptomyces spp.

    Manulis S et al (1994) Microbiology 140 ( Pt 5) : 1045-50.

3 Item(s)