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Data

Product overview

  • Name
    FFN511
  • Short description
    Novel fluorescent false neurotransmitter and VMAT2 substrate. Optical tracer for dopamine.
  • Biological description
    Novel fluorescent false neurotransmitter. VMAT2 substrate (IC50 = 1 µM for inhibition of 5-HT binding to VMAT2-containing membranes (comparable to dopamine)). Optical tracer for dopamine which labels dopamine presynaptic terminals in striatum. Compatible with GFP-based tags and other optical probes.
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one
  • Molecular Weight
    284.35
  • Molecular Formula
    C17H20N2O2
  • CAS Number
    1004548-96-2

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in water (25mM, 1eq HCl) and DMSO (5mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for FFN511

  • Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals.

    Gubernator et al (2009) Science 324(5933) : 1441-4
    PubMedID: 19423778
  • Dopamine release at individual presynaptic terminals visualized with FFNs.

    Zhang et al (2009) J Vis Exp doi: 10.3791/1562 : (3)
    PubMedID: 19721412
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