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Images Isoguvacine hydrochloride product vial image | Hello Bio
Isoguvacine hydrochloride product vial image | Hello Bio Biological Data Biological description Selective GABAA receptor agonist (IC50 = 5.6 µM). Less potent than GABA. Shows anti-epileptic actions.
Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride
Chemical structure
Molecular Formula C6 H9 NO2 .HCl
PubChem identifier 155107
SMILES C1CNCC=C1C(=O)O.Cl
InChi InChI=1S/C6H9NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H
InChiKey SUWREQRNTXCCBL-UHFFFAOYSA-N
References for Isoguvacine hydrochloride References are publications that support the biological activity of the product
Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures. Wahab A et al (2009) Epilepsy Res 86(2-3) : 113-23. Understanding your inhibitions: effects of GABA and GABAA receptor modulation on brain cortical metabolism. Nasrallah FA et al (2009) J Neurochem 108(1) : 57-71. Isoguvacine binding, uptake, and release: relation to the GABA system. White WF et al (1983) J Neurochem 40(6) : 1701-8. Isoguvacine binding, uptake, and release: relation to the GABA system. White WF et al (1983) J Neurochem 40(6) : 1701-8.
Selective GABAA receptor agonist
![Isoguvacine hydrochloride [68547-97-7] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0883.png "Isoguvacine hydrochloride [68547-97-7]")
Understanding purity and quality - a guide for life scientists
