Product overview

Name Isoliquiritigenin
Alternative names 4,2′,4′-Trihydroxychalcone
Purity >98%
Description Flavonoid with many biological actions
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Biological Data

Biological description Flavonoid with many biological actions. Also acts as a GABAA positive allosteric modulator and NLRP3 inflammasome activation inhibitor

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (75 mM), and in ethanol (20 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Molecular Weight 256.3
Chemical structure Isoliquiritigenin [961-29-5] Chemical Structure
Molecular Formula C15H12O4
CAS Number 961-29-5
PubChem identifier 638278
SMILES C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O
InChi InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
InChiKey DXDRHHKMWQZJHT-FPYGCLRLSA-N
MDL number MFCD00075907
Appearance Yellow solid

References for Isoliquiritigenin

References are publications that support the biological activity of the product
  • Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models

    Ramalingam et al (2018) Front Aging Neurosci 10 : 348
  • A Review: The Pharmacology of Isoliquiritigenin

    Peng et al (2015) Phytother Res. 29(7) : 969-77

2 Item(s)