Ivachtin

(HB1284)

Product overview

  • Name
    Ivachtin
  • Short description
    Potent caspase-3 inhibitor
  • Biological description
    Potent and reversible caspase-3 inhibitor (IC50 = 23 nM). Cell-permeable.
  • Biological action
    Inhibitor
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    2-[4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl]ethylacetate
  • Molecular Weight
    447.46
  • Molecular Formula
    C20H21N3O7S
  • CAS Number
    745046-84-8

Storing and Using Your Product

  • Storage instructions
    +4°C (desiccate)
  • Solubility overview
    soluble in DMSO (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Ivachtin

  • Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.

    Kravchenko DV et al (2005) J Med Chem 48(11) : 3680-3.
    PubMedID: 15916416

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