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Data

Product overview

  • Name
    Jervine
  • Short description
    Hedgehog signaling inhibitor. Directly binds to Smo.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1 1bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexad ecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H -benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1 H)-one
  • Molecular Weight
    425.6
  • Chemical structure
    Jervine |  [469-59-0]
  • Molecular Formula
    C27H39NO3
  • CAS Number
    469-59-0
  • PubChem identifier
    10098
  • SMILES
    O[C@H](C2)CC[C@@]1(C)C2=CC[C@]([C@@](CC[C@@]54O[C@@](C[C@H](C)CN6)([H])[C@]6([H])[C@H]5C)([H])C3=[C@@]4C)([H])[C@@]([H])1C3=O
  • InChiKey
    CLEXYFLHGFJONT-DNMILWOZSA-N

Storing and Using Your Product

  • Storage instructions
    -20°C
  • Solubility overview
    soluble in ethanol (50mM) or DMSO (20mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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