Product overview

  • Name
    K-252b
  • Short description
    Potent PKC and casein kinase II inhibitor
  • Biological description
    Potent protein kinase C (PKC) and casein kinase II inhibitor (IC50 = 38.3 nM at PKC). Inhibits neurotrophic factor and nerve growth factor.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    Staurosporine Aglycone
  • Molecular Weight
    453.45
  • Chemical structure
    K-252b  [99570-78-2]
  • Molecular Formula
    C26H19N3O5
  • CAS Number
    99570-78-2
  • PubChem identifier
    9846716
  • SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O

Storing and Using Your Product

  • Solubility overview
    soluble in DMSO (1mg/ml) or DMF (1mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for K-252b

  • K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

    Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71.
    PubMedID: 3759658
  • K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

    Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71.
    PubMedID: 3759658

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