Product overview

Name K-252b
Purity >98%
Description Potent PKC and casein kinase II inhibitor
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Biological Data

Biological description Potent protein kinase C (PKC) and casein kinase II inhibitor (IC50 = 38.3 nM at PKC). Inhibits neurotrophic factor and nerve growth factor.

Solubility & Handling

Solubility overview Soluble in DMSO (1mg/ml) or DMF (1mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name Staurosporine Aglycone
Molecular Weight 453.45
Chemical structure K-252b  [99570-78-2] Chemical Structure
Molecular Formula C26H19N3O5
CAS Number 99570-78-2
PubChem identifier 9846716
SMILES CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O

References for K-252b

References are publications that support the biological activity of the product
  • K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

    Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71.
  • K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.

    Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71.

2 Item(s)