KU 0063794
(HB2250)
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KU 0063794
(HB2250)- Data
- Support & Resources
Data
Product overview
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Name
KU 0063794
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Short description
Potent, selective mTOR inhibitor
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Biological description
Potent and selective mTOR inhibitor (IC50 = ~10 nM at mTORC1 and mTORC2). Shows little actvity at 76 other protein kinases or 7 lipid kinases. Cell permeable. Supresses cell viability and growth and by inducing cell cycle arrest and autophagy.
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Biological action
Inhibitor
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Purity
>97%
- Citations
Properties
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Chemical name
rel-5-[2-[(2R,6S)-2,6-dimethyl-4-mo rpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin -7-yl]-2-methoxybenzenemethanol
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Molecular Weight
465.54
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Molecular Formula
C25H31N5O4
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CAS Number
938440-64-3
Storing and Using Your Product
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Storage instructions
room temperature
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Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources
Reviews & Product Guides
Understanding purity and quality - a guide for life scientists Size: (159.38 KB)