L-DOPA methyl ester hydrochloride

(HB5354)
Technical documents: SDS CoA Datasheet

Product overview

Name L-DOPA methyl ester hydrochloride
Alternative names DME, LDME, Levodopa methyl ester, ST 41769, 3,4-Dihydroxyphenylalanine methyl ester
Purity >98%
Description

Water soluble L-DOPA derivative

Write Your Own Review
You're reviewing:L-DOPA methyl ester hydrochloride
Rate this item:

Images

L-DOPA methyl ester hydrochloride product vial image | Hello Bio

Biological Data

Biological description

Highly water-soluble derivative of L-DOPA, with better oral bioavailability, solubility and pharmacokinetic profile than L-DOPA. Exhibits anti-parkinsonian action.

Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in water (100 mM)

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name

Methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

Molecular Weight 247.68
Chemical structure  Chemical Structure
Molecular Formula C10H13NO4.HCl
CAS Number 1421-65-4
PubChem identifier 10131132
SMILES COC(=O)[C@H](CC1=CC(=C(C=C1)O)O)N.Cl
InChi InChI=1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H/t7-;/m0./s1
InChiKey WFGNJLMSYIJWII-FJXQXJEOSA-N
MDL number MFCD00038958
Appearance Off-white solid

References for L-DOPA methyl ester hydrochloride

References are publications that support the biological activity of the product
  • Development of a Hydrophobicity-Controlled Delivery System Containing Levodopa Methyl Ester Hydrochloride Loaded into a Mesoporous Silica

    Kiss et al (2021) Pharmaceutics 13(7) : 1039
  • Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat

    Lebel et al (2010) Neurobiol Dis. :
  • The effects on central dopamine function of chronic L-dopa (methyl ester hydrochloride) treatment of mice

    Tabar et al (1989) Pharmacol Biochem Behav. 139-46. : 33(1)

3 Item(s)