L-threo-Sphingosine C-18

(HB0388)

Product overview

  • Name
    L-threo-Sphingosine C-18
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor. D-erythro-sphingosine analog.
  • Alternative names
    L-threo-C18-sphingosine
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    2S-?amino-?4E-?octadecene-?1,?3S-?diol
  • Molecular Weight
    299.5
  • Chemical structure
    L-threo-Sphingosine C-18  [25695-95-8]
  • Molecular Formula
    C18H37NO2
  • CAS Number
    25695-95-8

Storing and Using Your Product

  • Solubility overview
    soluble in ethanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for L-threo-Sphingosine C-18

  • Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases.

    Mandon EC et al (1991) Eur J Biochem 198(3) : 667-74.
    PubMedID: 1646717
  • Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds.

    Merrill AH Jr et al (1989) Biochemistry 28(8) : 3138-45.
    PubMedID: 2742830

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