Product overview

Name L-threo-Sphingosine C-18
Alternative names L-threo-C18-sphingosine
Purity >98%
Description PKC inhibitor
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Biological Data

Biological description Protein kinase C (PKC) inhibitor. D-erythro-sphingosine analog.

Solubility & Handling

Solubility overview Soluble in ethanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol
Molecular Weight 299.5
Chemical structure L-threo-Sphingosine C-18  [25695-95-8] Chemical Structure
Molecular Formula C18H37NO2
CAS Number 25695-95-8

References for L-threo-Sphingosine C-18

References are publications that support the biological activity of the product
  • Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases.

    Mandon EC et al (1991) Eur J Biochem 198(3) : 667-74.
  • Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds.

    Merrill AH Jr et al (1989) Biochemistry 28(8) : 3138-45.

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