L-Cysteinesulfinic acid monohydrate

(HB0380)

Product overview

  • Name
    L-Cysteinesulfinic acid monohydrate
  • Short description
    mGlu / mGlu5a agonist
  • Biological description
    mGlu and mGlu5a receptor agonist in RGT cell lines. Also acts as a NMDA receptor agonist and PLD-coupled mGlu receptor agonist.
  • Alternative names
    L-CSA
  • Biological action
    Agonist
  • Our products in action

Properties

  • Molecular Weight
    171.17
  • Chemical structure
    L-Cysteinesulfinic acid monohydrate  [1115-65-7]
  • Molecular Formula
    C3H7NO4S.H2O
  • CAS Number
    1115-65-7

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in water (100mM)

References for L-Cysteinesulfinic acid monohydrate

  • Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.

    Kingston AE et al (1998) Neuropharmacology 37(3) : 277-87.
    PubMedID: 9681926
  • Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors.

    Gorman A et al (1994) Neuroscience 59(2) : 299-308.
    PubMedID: 8008194
  • L-cysteine sulfinic acid as an endogenous agonist of a novel metabotropic receptor coupled to stimulation of phospholipase D activity.

    Boss V et al (1994) Mol Pharmacol 45(6) : 1177-82.
    PubMedID: 8022410
  • Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

    Servitja JM et al (2003) Neuropharmacology 44(2) : 171-80.
    PubMedID: 12623215