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Linagliptin

(HB4637)
Data

Product overview

  • Name
    Linagliptin
  • Short description
    Highly potent, selective, competitive dipeptidyl-peptidase 4 inhibitor
  • Biological description
    Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione
  • Molecular Weight
    472.5
  • Chemical structure
    Linagliptin [668270-12-0]
  • CAS Number
    668270-12-0
  • InChiKey
    LTXREWYXXSTFRX-QGZVFWFLSA-N
  • Appearance
    White to off-white solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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