Product overview

  • Name
    L-NAME
  • Short description
    Non-selective NOS inhibitor
  • Biological description
    Non-selective nitric oxide synthase (NOS) inhibitor. Also inhibits cyclic GMP (IC50 = 3.1 μM). Methyl ester pro-drug of L-NNA. Displays hypertensive properties.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    Nomega-Nitro-L-arginine methyl ester hydrochloride
  • Molecular Weight
    269.69
  • Chemical structure
    L-NAME  [51298-62-5]
  • Molecular Formula
    C7H15N5O4.HCl
  • CAS Number
    51298-62-5
  • PubChem identifier
    135193
  • SMILES
    COC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N.Cl
  • InChi
    InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1
  • InChiKey
    QBNXAGZYLSRPJK-JEDNCBNOSA-N
  • MDL number
    MFCD00039052

Storing and Using Your Product

  • Storage instructions
    Room temperature
  • Solubility overview
    Soluble in water (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for L-NAME

  • L-NAME in the cardiovascular system - nitric oxide synthase activator?

    Kopincová J et al (2012) Pharmacol Rep 64(3) : 511-20.
    PubMedID: 22814004
  • Nitric oxide synthases: structure, function and inhibition.

    Alderton WK et al (2001) Biochem J 357(Pt 3) : 593-615.
    PubMedID: 11463332
  • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo.

    Rees DD et al (1990) Br J Pharmacol 101(3) : 746-52.
    PubMedID: 1706208

Reviews & Product Guides