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Product overview

  • Name
  • Short description
    Mitochondrial hexokinase inhibitor
  • Biological description
    Mitochondrial hexokinase inhibitor; inhibits glycolysis. Blocks CFTR channel currents (Kd = 58 µM). Shows antispermatogenic and antitumor actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
  • Molecular Weight
  • Chemical structure
    Lonidamine  [50264-69-2]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in ethanol (5mM) or DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Lonidamine

  • Mechanism of lonidamine inhibition of the CFTR chloride channel.

    Gong X et al (2002) Br J Pharmacol 137(6) : 928-36.
    PubMedID: 12411425
  • Lonidamine: basic science and rationale for treatment of prostatic proliferative disorders.

    Brawer MK (2005) Rev Urol 7 Suppl 7 : S21-6.
    PubMedID: 16986057
  • Recent studies on lonidamine, the lead compound of the antispermatogenic indazol-carboxylic acids.

    Gatto MT et al (2002) Contraception 65(4) : 277-8.
    PubMedID: 12020777
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