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Minocycline hydrochloride

(HB4617)
Data

Product overview

  • Name
    Minocycline hydrochloride
  • Short description
    Broad spectrum antibiotic. Potent microglial activation inhibitor.
  • Biological description
    Broad spectrum, blood-brain barrier permeable tetracycline antibiotic. Shows a variety of effects including anti-inflammatory, anti-angiogenesis and neuroprotective and neurorestorative effects in vivo. Potently inhibits microglial activation. Shown to suppress activation of human and mouse microglia stimulated with Aβ.
  • Alternative names
    MC
  • Biological action
    Antibiotic
  • Citations

Properties

  • Chemical name
    [4S-(4?,4a?,5a?,12a?)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
  • Molecular Weight
    493.94
  • Molecular Formula
    C23H27N3O7.HCl
  • CAS Number
    13614-98-7
  • PubChem identifier
    54685925
  • SMILES
    CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl
  • InChiKey
    WTJXVDPDEQKTCV-VQAITOIOSA-N
  • MDL number
    MFCD00083669
  • Appearance
    Yellow

Storing and Using Your Product

  • Storage instructions
    +4 °C
  • Solubility overview
    Soluble in DMSO (100 mM) and water (25 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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