Broad spectrum, blood-brain barrier permeable tetracycline antibiotic. Shows a variety of effects including anti-inflammatory, anti-angiogenesis and neuroprotective and neurorestorative effects in vivo. Potently inhibits microglial activation. Shown to suppress activation of human and mouse microglia stimulated with Aβ. Also allows formation of extended pluripotent stem (EPS) cells.
Solubility & Handling
Storage instructions
+4°C
Solubility overview
Soluble in DMSO (100 mM) and water (25 mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
These publications cite the use of Minocycline hydrochloride purchased from Hello Bio:
Astrocytic c-Jun N-terminal kinase-histone deacetylase-2 cascade contributes to glutamate transporter-1 decrease and mechanical allodynia following peripheral nerve injury in rats
Understanding purity and quality - a guide for life scientists