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Product overview

  • Name
    NF 449
  • Short description
    Potent, selective, competitive P2X receptor antagonist
  • Biological description
    Potent, selective and competitive P2X receptor antagonist. Selective for P2X1 receptors (IC50 values are 0.3 and 0.7 nM, 0.3, 1.8, 47 and >300 µM for P2X1, P2X1 + 5, P2X2 + 3, P2X3, P2X2 and P2X4 receptors respectively). Also inhibits FGFR3. Shows potential anti-cancer and anti-thrombotic actions.
  • Biological action
  • Citations


  • Chemical name
    4,4',4'',4'''-[Carbonylbis(imino-5,1,3-be nzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzen edisulfonic acid, octasodium salt
  • Molecular Weight
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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