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Product overview

  • Name
  • Short description
    L-type Ca2+ channel blocker
  • Biological description
    L-type Ca2+ channel blocker. Causes down regulation of NF-κB, proinflammatory cytokines and cell adhesion molecules. Reduces oxidative stress and smooth muscle cell proliferation and shows potential actions against atherosclerosis. Shows neuroprotective actions for dopaminergic neurones and acts as a vasodilator.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    Nifedipine  [21829-25-4]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    +4°C (desiccate)
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Nifedipine

  • Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.

    Daschil N et al (2014) Brain Res 1581 : 1-11.
    PubMedID: 25038562
  • Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB.

    S K S S et al (2012) Respir Physiol Neurobiol 183(1) : 26-34.
    PubMedID: 22627105
  • Nifedipine inhibits vascular smooth muscle cell proliferation and reactive oxygen species production through AMP-activated protein kinase signaling pathway.

    Sung JY et al (2012) Vascul Pharmacol 56(1-2) : 1-8.
    PubMedID: 21708289
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