Oleyloxyethyl Phosphorylcholine

(HB0472)

Product overview

  • Name
    Oleyloxyethyl Phosphorylcholine
  • Short description
    PLA2 inhibitor
  • Biological description
    Phospholipase A2 (PLA2) inhibitor (IC50 = 1.4 µM). Also inhibits ATP-induced histamine release. Cell permeable.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Molecular Weight
    477.7
  • Chemical structure
    Oleyloxyethyl Phosphorylcholine  [84601-19-4]
  • Molecular Formula
    C25H52NO5P
  • CAS Number
    84601-19-4
  • PubChem identifier
    5353846
  • SMILES
    CCCCCCCCC=CCCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C

Storing and Using Your Product

  • Solubility overview
    soluble in ethanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Oleyloxyethyl Phosphorylcholine

  • A novel phospholipase A2 activity in saliva of the lone star tick, Amblyomma americanum (L.).

    Bowman AS et al (1997) Exp Parasitol 87(2) : 121-32.
    PubMedID: 9326887
  • ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells.

    Lee YH et al (2001) Arch Pharm Res 24(6) : 552-6.
    PubMedID: 11794534

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