Oleyloxyethyl Phosphorylcholine

(HB0472)
Technical documents: Datasheet

Product overview

Name Oleyloxyethyl Phosphorylcholine
Purity >98%
Description PLA2 inhibitor
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Biological Data

Biological description Phospholipase A2 (PLA2) inhibitor (IC50 = 1.4 µM). Also inhibits ATP-induced histamine release. Cell permeable.

Solubility & Handling

Solubility overview Soluble in ethanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 477.7
Chemical structure Oleyloxyethyl Phosphorylcholine  [84601-19-4] Chemical Structure
Molecular Formula C25H52NO5P
CAS Number 84601-19-4
PubChem identifier 5353846
SMILES CCCCCCCCC=CCCCCCCCCOCCOP(=O)([O-])OCC[N+](C)(C)C

References for Oleyloxyethyl Phosphorylcholine

References are publications that support the biological activity of the product
  • ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells.

    Lee YH et al (2001) Arch Pharm Res 24(6) : 552-6.
  • A novel phospholipase A2 activity in saliva of the lone star tick, Amblyomma americanum (L.).

    Bowman AS et al (1997) Exp Parasitol 87(2) : 121-32.

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