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Pam3Cys-Ser-(Lys)4 trihydrochloride

(HB4015)
Data

Product overview

  • Name
    Pam3Cys-Ser-(Lys)4 trihydrochloride
  • Short description
    Selective Toll-like receptor1/2 (TLR1/TLR2) complex agonist
  • Biological description
    Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB.
  • Citations

Properties

  • Molecular Weight
    1619.7
  • CAS Number
    112208-04-5
  • InChiKey
    ZRKOETJPZDQIFB-OQOFFOABSA-N
  • Appearance
    Colorless powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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