Product overview

  • Name
    PETCM
  • Short description
    Caspase-3 activator
  • Biological description
    Caspase-3 activator. Inhibits ProT and stimulates apoptosome formation. Promotes Apaf-1 oligomerization. Shows apoptotic actions.
  • Biological action
    Activator
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    α-(Trichloromethyl)-4-pyridineethanol
  • Molecular Weight
    240.52
  • Molecular Formula
    C8H8Cl3NO
  • CAS Number
    10129-56-3

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in HCl (50mM, 1eq. HCl)

References for PETCM

  • Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.

    Jiang X et al (2003) Science 299(5604) : 223-6.
    PubMedID: 12522243
  • Direct activation of the apoptosis machinery as a mechanism to target cancer cells.

    Nguyen JT et al (2003) Proc Natl Acad Sci U S A 100(13) : 7533-8.
    PubMedID: 12808146

Reviews & Product Guides