In my cart

You have no items in your shopping cart.

Phloretin

(HB0500)
Data

Product overview

  • Name
    Phloretin
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor. PGF2a receptor antagonist (IC50 = 16 µM). Inhibits GLUT2 glucose transport. Shows apoptotic, antitumor, antioxidant and immunomodulatory actions.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Citations

Properties

  • Molecular Weight
    274.26
  • Chemical structure
    Phloretin  [60-82-2]
  • Molecular Formula
    C15H14O5
  • CAS Number
    60-82-2
  • PubChem identifier
    4788
  • SMILES
    OC1=CC=C(CCC(=O)C2=C(O)C=C(O)C=C2O)C=C1

Storing and Using Your Product

  • Solubility overview
    soluble in ethanol or methanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Phloretin

  • Immunomodulation of phloretin by impairing dendritic cell activation and function.

    Lin CC et al (2014) Food Funct 5(5) : 997-1006.
    PubMedID: 24651121
  • Phloretin-induced apoptosis in B16 melanoma 4A5 cells and HL60 human leukemia cells.

    Kobori M et al (1999) Biosci Biotechnol Biochem 63(4) : 719-25.
    PubMedID: 10361685
  • Phloretin as an antagonist of prostaglandin F2 alpha receptor in cultured rat astrocytes.

    Kitanaka J et al (1993) J Neurochem 60(2) : 704-8.
    PubMedID: 8093482
  • In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter.

    Wu CH et al (2009) Int J Cancer 124(9) : 2210-9.
    PubMedID: 19123483
Support & Resources

Reviews & Product Guides