Product overview

  • Name
    PHTPP
  • Short description
    Selective ERβ estrogen receptor antagonist
  • Biological description
    Selective ERβ estrogen receptor antagonist. Shows 36-fold selectivity for ERβ over ERα. Active in vivo.
  • Biological action
    Antagonist
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol
  • Molecular Weight
    423.31
  • Chemical structure
    PHTPP
  • Molecular Formula
    C20H11F6N3O
  • CAS Number
    805239-56-9

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for PHTPP

  • Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.

    Compton DR et al (2004) J Med Chem 47(24) : 5872-93.
    PubMedID: 15537344
  • Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress.

    Weiser MJ et al (2009) Endocrinology 150(4) : 1817-25.
    PubMedID: 19074580

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