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PI 103 hydrochloride

(HB2797)
Data

Product overview

  • Name
    PI 103 hydrochloride
  • Short description
    Potent dual PI3-K/mTOR inhibitor
  • Biological description
    Potent dual PI3-K/mTOR inhibitor with selectivity for PI3K family (IC 50 values are 2, 3, 3 and 15 nM at p110α, p110β, p110δ and p110γ and 20 and 83 nM at mTORC1 and mTORC2 respectively). Also shows activity at DNA-PK (IC50 = 14 nM). Shows antitumor activity and inhibits tumor cell invasion. Active in vivo.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    3-[4-(4-Morpholinylpyrido[3',2':4,5]f uro[3,2-d]pyrimidin-2-yl]phenol hydrochloride
  • Molecular Weight
    384.82
  • Molecular Formula
    C19H16N4O3.HCl
  • CAS Number
    371935-79-4

Storing and Using Your Product

  • Storage instructions
    +4°C (desiccate)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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