Potent dual PI3-K/mTOR inhibitor with selectivity for PI3K family (IC 50 values are 2, 3, 3 and 15 nM at p110α, p110β, p110δ and p110γ and 20 and 83 nM at mTORC1 and mTORC2 respectively). Also shows activity at DNA-PK (IC50 = 14 nM). Shows antitumor activity and inhibits tumor cell invasion. Active in vivo.
Solubility & Handling
Storage instructions
+4°C (desiccate)
Storage buffer
Soluble in DMSO (20mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists