Piceatannol

(HB0505)

Product overview

  • Name
    Piceatannol
  • Short description
    Syk tyrosine kinase / JAK-1 inhibitor
  • Biological description
    Syk tyrosine kinase inhibitor (IC50 = 1.53 µM). Also JAK-1 inhibitor. Analog of resveratrol. Shows many biological actions such as growth-inhibitory, anti-oxidant, anti-inflammatory, cardiovascular and pro-apoptotic effects.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    3,5,3',4'-Tetrahydroxystilbene
  • Molecular Weight
    244.3
  • Chemical structure
    Piceatannol  [10083-24-6]
  • Molecular Formula
    C14H12O4
  • CAS Number
    10083-24-6
  • PubChem identifier
    667639
  • SMILES
    C1=CC(=C(C=C1C=CC2=CC(=CC(=C2)O)O)O)O

Storing and Using Your Product

  • Solubility overview
    soluble in DMSO (10mg/ml) or DMF

References for Piceatannol

  • Biological activity of piceatannol: leaving the shadow of resveratrol.

    Piotrowska H et al (2012) Mutat Res 750(1) : 60-82.
    PubMedID: 22108298
  • Piceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.

    Chen WP et al (2009) Br J Pharmacol 157(3) : 381-91.
    PubMedID: 19371352
  • Piceatannol inhibits melanogenesis by its antioxidative actions.

    Yokozawa T et al (2007) Biol Pharm Bull 30(11) : 2007-11.
    PubMedID: 17978467

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