PKA Inhibitor IV

(HB0509)

Order: HB0509

Pack	Price	Qty
500μg	$282

(HB0509)

Data

Product overview

Name
PKA Inhibitor IV
Short description
Potent, selective PKA inhibitor
Biological description
Potent and selective protein kinase A (PKA) inhibitor (K_i = 2.8 nM).
Alternative names
PKI (5-24)
Biological action
Inhibitor
Citations
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Chemical name
L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-a-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid
Molecular Weight
2222.4
Molecular Formula
C₁₈H₂₄N₄O₃S.2HCl
CAS Number
99534-03-9
PubChem identifier
0
SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)O)C(C)O)[C@@H](C)CC)C(C)O)C(=O)N[C@@H](Cc3[nH]cnc3)C(=O)N[C@@H](CC(O)=O)C(O)=O

Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Sargaquinoic acid promotes neurite outgrowth via protein kinase A and MAP kinases-mediated signaling pathways in PC12D cells.

Kamei Y et al (2003) Int J Dev Neurosci 21(5) : 255-62.
PubMedID: 12850058
Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat.

Boylan JM et al (2001) J Biol Chem 276(48) : 44457-63.
PubMedID: 11574531

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