Product overview

Name PLX4720
Purity >99%
Description Potent and selective cell permeable B-Raf and C-Raf inhibitor
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Biological Data

Biological description Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Molecular Weight 413.8
Chemical structure PLX4720 [918505-84-7] Chemical Structure
CAS Number 918505-84-7
InChiKey YZDJQTHVDDOVHR-UHFFFAOYSA-N
Appearance Off-white solid